Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group KP- propofol and ketamine (ketofol): Induction dose: A 20 ml syringe will be prepared by mixing 10 ml of propofol (10 mg/ml) and 10 ml of ketamine (10 mg/ml), resulting in each ml
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Surgery duration less than 90 min ASA physical status I-II BMI less than 35kg/ m2 Willingness to participate provide written informed consent
Exclusion criteria
Exclusion criteria: Known psychiatric illness or drug allergy Ischemic heart disease Anticipated difficult airway Raised ICT, IOP, glaucoma Pregnant or lactating women Chronic opiod use / substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation timeTimepoint: At 0 minutes (discontinuation of anesthesia) and every minute thereafter up to 15 minutes, until extubation is achieved. | — |
Secondary
| Measure | Time frame |
|---|---|
| Emergence time(from the discontinuation of the anesthetic agent till the time the patient opened their eyes in response to verbal commands), Recovery time (from discontinuation of the anesthetic agent till the time the patient uttered his/her name on verbal questioning), Cough score, agitation score,Aldrete score Hemodynamic parameters, Total amount of anesthetic drug used intraoperatively (fentanyl, propofol, ketamine) Pain score, rescue analgesia requirement, PONV incidence, emergence delirium.Timepoint: From Intraoperative period till two hours postoperatively. Intraoperative period (for drug use & vitals) At extubation (0 minutes) for emergence time & recovery time 15 minutes postoperatively (Aldrete score, agitation, cough, vitals) Every 30min postoperatively pain score, rescue analgesia. 30 minutes postoperatively (Aldrete score repeated) 1 hour postoperatively 2 hours postoperatively (pain, rescue analgesia, PONV,emergence delirium) | — |
Countries
India
Contacts
Public ContactDR BHUPENDRA SINGH
AIIMS Gorakhpur
Outcome results
None listed