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Comparing Pain Relief After Root Canal Cleaning of Lower Molars Using Steroid Injection or Laser Treatment

comparing the post operative pain after submucosal Dexamethasone injection and low level laser therapy following biomechanical preparation of Mandibular Molars - A Randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091828
Enrollment
117
Registered
2025-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Submucosal Dexamethasone Injection (Dexona): administering submucosal dexamethasone injection (1ml) 4mg in the buccal vestibule close to the root apex of the targeted tooth with 5ml 30

Sponsors

Dr Vishakha Pala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients requiring root canal treatment of mandibular 1st and 2nd molars 2 Patients diagnosed with irreversible pulpitis and/or apical periodontitis 3 Teeth which are tender on percussion 4 Teeth with spontaneous pain or lingered by cold or heat 5 Teeth with mature apex 6 Teeth with mobility less than 1mm in either direction 7 PAI Index score of 2 or 3 8 Pre-operative tooth and percussion pain of less than 56 mm on a 170 mm visual analogue scale (VAS)

Exclusion criteria

Exclusion criteria: 1 Patients on aspirin 2 Patients with other pulpal diagnosis 3 Patients with a history of analgesic intake (antibiotics, NSAIDs, opioids or corticosteroids) during 12 hours prior to treatment 4 Presence of complex anatomy of the root (severe curvature more than 25 degrees) 5 Calcified/obstructed canals on radiographs 6 Very long roots 7 Internal/ External root resorption 8 Teeth with open apex 9 Teeth with procedural errors 10 Presence of any defect in the root- caries, restoration, previously endodontically treated, root resorption, craze lines and fracture 11 Severely damaged teeth 12 Teeth with severe periodontal disease 13 Teeth with periodontal probing depth more than 3 mm 14 Teeth associated with swelling, sinus tract, presence of a radiographic lesion 15 Tooth hypersensitivity to percussion 16 Absence of occlusal contact

Design outcomes

Primary

MeasureTime frame
Comparing The Post Operative Pain following biomechanical preparation After Submucosal Dexamethason Injection And Low Level Laser Therapy.Timepoint: Telephonic evaluation of Postoperative pain will be done using: 170 mm Heft-Parkar Visual Analogue Scale (VAS) Pain assessment questionnaire: including the duration of pain, record of medications taken and other complaints at 6 , 12 , 24 , 48 and 72 hours at 72 hours postoperatively Patient will be recalled for follow-up and evaluated for intra-oral complications and percussion test will be done to check the periapical status.

Secondary

MeasureTime frame
evaluate the degree of post-operative pain following biomechanical preparation in non surgical root canal treatment of mandibular molars with irreversible pulpitis and/or apical periodontitis in conjunction with Submucosal Dexamethasone administration.Timepoint: Telephonic evaluation of Postoperative pain will be done using: 170 mm Heft-Parkar Visual Analogue Scale (VAS) Pain assessment questionnaire: including the duration of pain, record of medications taken and other complaints at 6 , 12 , 24 , 48 and 72 hours at 72 hours postoperatively Patient will be recalled for follow-up and evaluated for intra-oral complications and percussion test will be done to check the periapical status. ;evaluate the degree of post-operative pain following biomechanical preparation in non surgical root canal treatment of mandibular molars with irreversible pulpitis and/or apical periodontitis in conjunction with Low level Laser TherapyTimepoint: Telephonic evaluation of Postoperative pain will be done using: 170 mm Heft-Parkar Visual Analogue Scale (VAS) Pain assessment questionnaire: including the duration of pain, record of medications taken and other complaints at 6 , 12 , 24 , 48 and 72 hours at 72 hours postoperatively Patient will be recalled for follow-up and evaluated for intra-oral complications and percussion test will be done to check the periapical status.

Countries

India

Contacts

Public ContactDr. Vishakha Pala

Manubhai Patel Dental College And Hospital

aroraankit24@gmail.com9033975629

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026