FindTrial
Sign In

Effect of Dexmedetomidine on Succinylcholine-Induced Fasciculation and Myalgia during Anaesthesia in ENT surgeries

Effect of infusion of Dexmedetomidine on Succinylcholine induced fasciculation and myalagia during General Anaesthesia in ENT surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091816
Enrollment
60
Registered
2025-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dexmedetomidine Group: The administration of intravenous dexmedetomidine (0.5 g/kg diluted in 20 ml of saline over 10 minutes) in 30 patients was done to evaluate its effectiveness in

Sponsors

Datta Meghe Institute of Higher Education and Research Wardha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Weighing between 40- 80 kg Without comorbidities Scheduled for elective short duration surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: Hypertension or ischemic heart disease Increased intracranial or intraocular pressure Anticipated difficult airways according to LEMON criteria Pregnant or currently breastfeeding women Diabetes mellitus

Design outcomes

Primary

MeasureTime frame
Incidence and severity of fasciculations after succinylcholine administration, assessed using Mingus ML grading scale. Incidence and severity of post-operative myalgia (POM) at 30 and 45 minutes post-extubation, assessed using Harvey et al. grading scale.Timepoint: Incidence and severity of fasciculations after succinylcholine administration, assessed using Mingus ML grading scale. Incidence and severity of post-operative myalgia (POM) at 30 and 45 minutes post-extubation, assessed using Harvey et al. grading scale.—

Secondary

MeasureTime frame
Hemodynamic changes (Heart Rate, SBP, DBP, MAP) at baseline and various time points (T1-T6). Quality of intubation conditions (satisfactory, fair, poor). Incidence of adverse effects such as hypotension, bradycardia, nausea, vomiting, and need for intervention. Requirement for additional neuromuscular blockade agents (vecuronium administration and dose adjustments). Post-operative analgesic requirement and need for additional pain management. Let me know if you need any modifications or additions.Timepoint: At intra op and 30 and 45 minutes post-extubation,—

Countries

India

Contacts

Public ContactDr kavya praneetha

Jawaharlal Nehru Institute of Medical Sciences

Jayashree_sen@rediffmail.com09813061192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026