Health Condition 1: O244- Gestational diabetes mellitus
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Dr PREETI GOSWAMI
Eligibility
Inclusion criteria
Inclusion criteria: Singleton Pregnancy, Pregnant women diagnosed with GDM as per DIPSI guidelines (non-fasting Oral Glucose Tolerance Test (OGTT) with 75g of glucose equal to or more than 140 mg per dl after 2 hours) Gestationally matched normal pregnant women in third trimester (equal to or more than 28 weeks) with non-fasting Oral Glucose Tolerance Test (OGTT) with 75g of glucose less than 140 mg per dl after 2 hours
Exclusion criteria
Exclusion criteria: Patients with history of or known case of diabetes mellitus, chronic hypertension, renal or cardiovascular disease, autoimmune disease, IUD (Intrauterine Death) will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean serum VEGF levels in GDM and Non GDM pregnant women in third trimester equal to or more than 28 weeks Histomorphological changes in placenta in GDM and normal pregnancies in third trimester equal to or more than 28 weeks Timepoint: outcomes will be measured once once at baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in mean serum levels of VEGF in Gestational Diabetes Mellitus & normal pregnant women in third trimester equal to or more than 28weeks Comparison of histomorphological changes in placenta in Gestational Diabetes Mellitus & normal pregnancies in third trimester equal to or more than 28 weeks Association of maternal serum VEGF levels with placental histomorphological changes in Gestational Diabetes Mellitus pregnanciesTimepoint: outcomes will be measured once at baseline | — |
Countries
India
Contacts
Public ContactDr PREETI GOSWAMI
MAULANA AZAD MEDICAL COLLEGE
Outcome results
None listed