Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Aprotinin: Injection Aprotinin 2ml administered submucosally just before the incision single dose.Total duration is single administration on the day of surgery only
Intervention2: Hyalu
Sponsors
All India Institute of Medical Sciences Rajkot
Eligibility
Inclusion criteria
Inclusion criteria: Healthy ambulatory patients reporting to the Department of Dentistry, AIIMS Rajkot requiring removal of single impacted lower third molars which necessitates mucoperiosteal flap elevation, buccal bone guttering with or without sectioning of tooth, Age between 18-50 years, slight and moderate difficult impaction based on radiographs.
Exclusion criteria
Exclusion criteria: Patients with systemic diseases, pregnancy and breast-feeding or any other medicinal therapy that could interfere with healing process, use of any antibiotic or any anti-inflammatory drug within 1 week period, patient with preoperative swelling, reduced mouth opening, any abusive habits like tobacco chewing, alcohol consumption and smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative facial swelling measured in millimeters using linear facial measurements.Timepoint: Baseline(preoperatively),72 hrs, 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in interincisal mouth opening (in mm)Timepoint: Baseline(preoperatively),72 hrs, 7 days;Reduction in pain measured using Visual Analog Scale (VAS)Timepoint: Baseline(preoperatively),72 hrs, 7 days | — |
Countries
India
Contacts
Public ContactDr Shreeya Sharma
All India Institute of Medical Sciences, Rajkot, Gujarat
Outcome results
None listed