Health Condition 1: H042- Epiphora
Conditions
Interventions
Intervention1: 5 IU of BOTOX-BOTULINUM TOXIN A: Botulinum injection: Participants diagnosed with Functional epiphora will be given the botulinum toxin injection(BOTOX-A)into palpebral lobe of the lacr
Sponsors
Centre For Sight Eye Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18 years and above (Both Males and Females included) 2. Patients diagnosed with Functional epiphora. 3. Presenting with excessive watering with syringing being patent 4. Patients who have given informed consent 5. Willing to complete the treatments and follow up regularly
Exclusion criteria
Exclusion criteria: 1. Previous hypersensitivity to botulinum toxin or human albumin 2. Eyelid infections like blepharitis, meibomian gland dysfunction. 3. Neuromuscular junction disorders 4. Ocular motility defects 5. Active intraocular inflammation, allergy or infection. 6. Ocular surface infections and inflammations. 7. History of dry eyes 8. Eyelid structural abnormality 9. Pregnancy 10. Lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the effectiveness of botulinum toxin injection into the lacrimal gland in reducing symptoms of functional epiphora, as measured by changes in the TEARS and MUNK scores.Timepoint: Baseline, One Month and Three Months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess patient satisfaction and subjective improvement in tearing symptoms following treatment. To evaluate the duration of effect and time to recurrence of symptoms after injection. To monitor and document any adverse effects or complications associated with botulinum toxin injectionsTimepoint: 0, 1 and 3 months Follow Up | — |
Countries
India
Contacts
Public ContactDr Piyush Bajaj
Centre For Sight Eye Hospital
Outcome results
None listed