A comparison of 2 medicine for assessing quality of intubation (insertion of breathing tube in windpipe)

Randomized prospective study to compare intubating conditions with cis-atracurium or atracurium under sevoflurane induction using train of four neuromuscular monitoring in adult patients undergoing elective surgery. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/091623

Enrollment

Registered

2025-07-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: To evaluate intubating conditions using train of four neuromuscular monitoring: TOF Monitoring will be done every 30 seconds during sevoflurane and after giving loading dose of nondepol

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1 & 2 PATIENTS UNDERGOING ELECTIVE SURGERY WITH INFROMED CONSENT.

Exclusion criteria

Exclusion criteria: PATIENTS UNDER FOLLOWING CONDITIONS:- 1.PATIENTS REFUSAL 2.PREGNANCY 3.COAGULOPATHY 4.ANTICIPATED DIFFICULT AIRWAY 5.ANY SEVERE SYSTEMIC DISEASE

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the intubating conditions and quality of neuromuscular blockade using train of four.Timepoint: Intubating conditions and neuromuscular blockade will be assessed intaoperatively at baseline.	—

Secondary

Measure	Time frame
To compare systemic effect of cis-atracurium and atracurium on hemodynamic parameters (viz. heart rate, systolic and diastolic blood pressure, oxygen saturation)Timepoint: hemodynamic parameters (heart rate; blood pressure, SPO2) will also be noted every 1min till 10minutes and every 2 min. till next 20 minutes to look for the effect of drugs on heart rate, blood pressure	—

Countries

India

Contacts

Public ContactDr Prateek Rastogi

Lala Lajpat Rai Memorial Medical College Meerut

drvipindhama@yahoo.com9760014177

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026