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Comparing Inj tranexamic acid with PRP in patients with melasma to find out which one has better outcome.

A comparative study to evaluate the efficacy of intralesional tranexamic acid versus intralesional platelet rich plasma in the treatment of melasma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091564
Enrollment
44
Registered
2025-07-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

Intervention1: Inj Tranexamic acid: 4 mg/ml of TXA,intradermal injections of TXA was administered over the hyper-pigmented patches, separating each prick with a 1 cm distance injecting one unit from i

Sponsors

Ashrita Krishna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Either gender 2) Age range of 20 to 50 years 3)Patients suffering from melasma. 4)Patients who didn t respond to conventional topical therapy for melasma

Exclusion criteria

Exclusion criteria: 1)Pregnancy and lactation 2)patients with known platelet dysfunction 3)Those with prior history of allergy to tranexamic acid (may june) 4)Intake of any photosensitizing drugs 5) Known allergy to TXA. 6) Women on oral contraceptive pills and hormone replacement therapy. 7) Patients on any topical therapy for melasma in the past 3 months. 8) Critical thrombocytopenia less than 50,000/mcl. 9)Any history of hemodynamic instability.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of intralesional Tranexamic acid versus intralesional Inj platelet rich plasma in the treatment of melasma. Timepoint: 20 weeks

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactAshrita Krishna

Hassan Institute Of Medical Sciences

drsureshhsn@gmail.com9480303929

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026