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To decrease mortality rate of adults patients admitted in a ICU with acute respiratory failure by minimising ventilation induced lung injury.

TO EVALUATE EFFECT OF MECHANICAL POWER DIRECTED LUNG PROTECTIVE VENTILATION STRATEGY ON TREATMENT OUTCOME IN PATIENTS WITH ACUTE RESPIRATORY FAILURE- A PROSPECTIVE STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/091554
Enrollment
100
Registered
2025-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: Mechanical power guided lung protective ventilation: Lung protective ventilation strategy is used for ventilation of adult patients with acute respiratory failure using the formula of m

Sponsors

FORTIS ESCORTS HEART INSTITUTE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Acute respiratory failure (ARF), defined as the ratio of partial pressure of oxygen (PaO2) to fraction of inspired oxygen (FiO2) less than 300 mmHg on admission, who will receive invasive mechanical ventilation for more than 48 hrs.

Exclusion criteria

Exclusion criteria: 1. Received treatment with extracorporeal life support; 2. Age less than 18 years; or 3. Mechanical power = 10 J/min on admission (with a possible lower risk of lung injury)

Design outcomes

Primary

MeasureTime frame
MortalityTimepoint: baseline,4 weeks—

Secondary

MeasureTime frame
Mechanical powerTimepoint: baseline, after 24 hours—

Countries

India

Contacts

Public ContactPUSHPA PRIYADARSHANI

FORTIS ESCORTS HEART INSTITUTE, DEPARTMENT OF CRITICAL CARE MEDICINE, DELHI

drpushpa23@gmail.com8130041896

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026