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Effects of Dexmedetomidine on Prevalence of Succinylcholine induced Fasciculations and Postoperative Myalgia A Randomized, controlled, double blinded study

Effects of dexmedetomidine on prevalence of succinylcholine induced fasciculations and post operative myalgia A randomized , controlled, double blinded study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091537
Enrollment
50
Registered
2025-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Patients of this group will receive Inj Dexmedetomidine 0.25mcg per kg body weight in 100 ml saline over a period of 15 mins intravenously before induction of anaesthes

Sponsors

Department of Anaesthesia School of medical sciences and research Sharda University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for any elective surgery under general anaesthesia with endotracheal intubation ASA class I and II Age 18-60 years Both genders

Exclusion criteria

Exclusion criteria: Patients already taking steroids or analgesics or antiemetic and sedatives preoperatively for any clinical condition Patients with past history of chronic pain Patients having history of endocrine or cardiovascular or renal or CNS disease Patients allergic to study drugs Contraindication of succinylcholine for example High potassium level extensive burn renal failure or soft tissue injury BMI more than 30 kg meter square

Design outcomes

Primary

MeasureTime frame
Prevalence of Succinylcholine induced Postoperative Myalgia following intravenous administration of DexmedetomidineTimepoint: Perioperative

Secondary

MeasureTime frame
To observe and compare the grades of fasciculations and Postoperative Myalgia To compare the changes in the levels of serum potassium To find out the relationship between fasciculations and serum potassium levels and myalgia To compare the heart rate and systolic blood pressure in two groupsTimepoint: Perioperative

Countries

India

Contacts

Public ContactDr Shivika Nath

School of Medical Sciences and Research Sharda hospital Sharda University

mahendra.kumar@sharda.ac.in8287188449

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026