Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients or Relatives willing to give consent, Hemodynamically unstable patients, Mean arterial pressure less than 65 mmHg, need for any vasopressor or ionotropic support, blood lactate levels more than 2 mmol per litre, urine output less than 0.5mlper kg per hr for more than 2hr, tachycardia more than 100 bpm, Signs of hypoperfusion.
Exclusion criteria
Exclusion criteria: Poor cardiac echogenicity, Cardiac arrythmias at the time of study, Aortic valve disease, Contraindications of PLR (Intracranial hypertension, Intra-abdominal hypertension), Venous stasis (DVT),
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare changes in Stroke Volume in response to fluid challenge and passive leg raisingTimepoint: baseline, 15 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Measure & compare percentage changes in mean value, in response to the PLR test & FC test in mean arterial pressureTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in ejection fractionTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in heart rateTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in IVC diameterTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in Cardiac IndexTimepoint: baseline , 15 minutes | — |
Countries
India
Contacts
ESIC Hospital And PGIMSR