Skip to content

Using leg raise and heart ultrasound to see if patients need more fluids

Assessment of fluid responsiveness by analyzing stroke volume change with Transthoracic echocardiography on passive leg raising test in hemodynamically unstable patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/091519
Enrollment
93
Registered
2025-07-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Harsh Kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients or Relatives willing to give consent, Hemodynamically unstable patients, Mean arterial pressure less than 65 mmHg, need for any vasopressor or ionotropic support, blood lactate levels more than 2 mmol per litre, urine output less than 0.5mlper kg per hr for more than 2hr, tachycardia more than 100 bpm, Signs of hypoperfusion.

Exclusion criteria

Exclusion criteria: Poor cardiac echogenicity, Cardiac arrythmias at the time of study, Aortic valve disease, Contraindications of PLR (Intracranial hypertension, Intra-abdominal hypertension), Venous stasis (DVT),

Design outcomes

Primary

MeasureTime frame
Compare changes in Stroke Volume in response to fluid challenge and passive leg raisingTimepoint: baseline, 15 minutes

Secondary

MeasureTime frame
Measure & compare percentage changes in mean value, in response to the PLR test & FC test in mean arterial pressureTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in ejection fractionTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in heart rateTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in IVC diameterTimepoint: baseline , 15 minutes;Measure & compare percentage changes in mean value, in response to the PLR test & FC test in Cardiac IndexTimepoint: baseline , 15 minutes

Countries

India

Contacts

Public ContactDr Divya Sethi

ESIC Hospital And PGIMSR

divyasth@gmail.com9891230700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026