Health Condition 1: O- Medical and Surgical Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Ropivacaine
: The patients will be randomized into two equal groups of 35 patients each.
Group N: Laparoscopic cholecystectomy + Irrigation of gallbladder bed with 20 mL normal saline.
Sponsors
Moksha Joshi
Eligibility
Inclusion criteria
Inclusion criteria: The patients who were willing to participate in study and had given written, valid and informed consent. Age - 18-65 years Patients posted for laparoscopic cholecystectomy American Society of Anaesthesiologist grade I and II Patients belonging to either gender
Exclusion criteria
Exclusion criteria: Patient refusal to be part of the study. Patients with known allergies or contraindications to ropivacaine, the agent used for gallbladder bed irrigation. Pregnancy or Lactation: Pregnant or lactating patients, as the safety of ropivacaine use during pregnancy and lactation, is not established. Chronic Respiratory Conditions; Severe Cardiovascular Disease; Severe Liver or kidney disease; acute cholecystitis, choledocholithiasis History of Allergic Reactions; Current Medications; Patients currently taking medications that may interact with ropivacaine (eg Fluvoxamine, cimetidine, ciprofloxacin, ketoconazole, verapamil, amiodarone) or affect pulmonary function particularly medications that influence neuromuscular function (eg aminoglycosides, magnesium, or chronic steroids) or respiratory depression (eg Opioids, benzodiazepines, barbiturates)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1, FVC, FEF 25-75Timepoint: Baseline, 6 hours, 8 hours, 12 hours, 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale, BHT, SBC, Cough test Timepoint: Baseline, 6hours, 8 hours, 12 hours, 24 hours | — |
Countries
India
Contacts
Public ContactMoksha Joshi
Grant Government Medical College
Outcome results
None listed