Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Intravenous dexmedetomidine
bolus of 1 mcg/kg (diluted to 20
ml normal saline) in infusion
over 10min, followed by
lidocaine bolus of 1.0 mg/kg
(diluted to 5ml of
Sponsors
Government Medical College and Hospital, Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 years to 65 years. 2.Patients undergoing laparoscopic cholecystectomy. 3.American Society of Anaesthesiologists (ASA) Grade I and II. 4.Body Mass Index (BMI) more than 18 and less than 35 kg/m2.
Exclusion criteria
Exclusion criteria: 1.Patients with coagulopathy and platelet disorders. 2.Contraindication or allergy to study drugs. 3.Pregnant and lactating women. 4.Severe cardiovascular, respiratory, neurological or metabolic disease. 5.Inability of the patient to understand the QoR -15 questionnaire. 6.Patients with baseline heart rate less than 60 beats/minute.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparison of postoperative quality of recovery score in patients receiving opioid based anaesthesia vs. opioid free anaesthesia in laproscopic cholecystectomyTimepoint: 24 hours post-operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the post operative pain scoreTimepoint: 30 min, 1 hour, 2 hour, 6 hour, 24 hour after surgery;To compare the postoperative Ramsay sedation score in post anaesthesia care unitTimepoint: 15 min, 30 min, 45 min, 1 hour after surgery;To compare the time of discharge from post anaesthesia care unit to the wardTimepoint: 1 to 2 hour | — |
Countries
India
Contacts
Public ContactDr Jasveer Singh
Government Medical College & Hospital, Chandigarh
Outcome results
None listed