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COMPARATIVE EVALUATION OF PLATELET RICH CONCENTRATES(L-PRF AND A-PRF) IN EXTRACTED TOOTH SOCKETS AND THEIR EFFECT ON ORTHODONTIC TOOTH MOVEMENT -A RANDOMIZED CONTROLLED STUDY

A COMPARATIVE EVALUATION OF THE EFFECT OF ADVANCED PLATELET RICH FIBRIN AND LEUKOCYTE - PLATELET RICH FIBRIN ON ORTHODONTIC TOOTH MOVEMENT: A RANDOMIZED CONTROLLED STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091427
Enrollment
96
Registered
2025-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: LEUKOCYTE RICH-PLATELET RICH FIBIRN(L-PRF) PLACEMENT: POST EXTRACTION LEUKOCYTE RICH-PLATELET RICH FIBIRN(L-PRF) WILL BE PLACED IN THE SOCKET AND THE SOCKET WILL BE SUTURED. Interventio

Sponsors

DR ANSH THAKKAR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i.Patients requiring fixed orthodontic treatment ii.Good oral hygiene and healthy periodontium iii.Patients whose treatment plan requires extraction of all 1st premolars iv.Age group- 15-30 years of age v.No previous history of orthodontic treatment

Exclusion criteria

Exclusion criteria: i.Patients who do not give consent for the study ii.Poor oral hygiene iii.Patients with any deleterious habits (smoking, alcohol, tobacco chewing) iv.Patients taking medications that could interfere with orthodontic tooth movement (NSAIDs, cortisone, bisphosphonates, anticoagulants and hormones like oestrogen, thyroid). v.Systemic illnesses like uncontrolled Diabetes mellitus, AIDS, patients on medication like phenytoin, or immunosuppressants.

Design outcomes

Primary

MeasureTime frame
Evaluate and Compare effect of Advanced-Platelet rich fibrin , Leukocyte rich -Platelet Rich Fibrin and placebo control on orthodontic tooth movement.Timepoint: Patient will be recalled every month (T1, T2 T3, T4) and study models will be made to check for amount of canine retraction measured from distal surface of canine to mesial surface of 2nd premolar with the help of Digital Vernier Caliper.—

Secondary

MeasureTime frame
Evaluate and Compare effect of Advanced-Platelet rich fibrin , Leukocyte rich -Platelet Rich Fibrin and placebo control on socket healing and pain control.Timepoint: Patient will be asked for pain post extraction and recalled every month (T1, T2 T3, T4) and checked for socket healing.—

Countries

India

Contacts

Public ContactDR ANSH THAKKAR

MANUBHAI PATEL DENTAL COLLEGE AND HOSPITAL

padmaja2216@yahoo.co.in9033975429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026