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Comparing Dexmedetomidine with lignocaine to check post-extubation cough reflex

Supra and subglottic instillation of dexmedetomidine for prevention of coughing during emergence from general anaesthesia : A comparison with lignocaine . - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091424
Enrollment
170
Registered
2025-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine Group: 2% Lignocaine at a dose of 1.5mg/kg of body weight via the subglottic port of the TuoRen Supra/subglottic Injectable endotracheal tube Duration - 15 minutes before Ext

Sponsors

DR HARSHA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Consent for participation 2. Scheduled for elective surgery under genaral anaesthsia

Exclusion criteria

Exclusion criteria: Refusal of Patient. 2. With Known contraindication and sensitivity of study drugs 3. History of asthma or COPD 4. Who requires post op ventilation 5. Anticipated difficult airway 6. history of tracheal surgery

Design outcomes

Primary

MeasureTime frame
To assess the incidence and severity of coughing during emergence from general anesthesiaTimepoint: Time POINT - JUST AFTER EXTUBATION, 1min post extubation, 2 min post extubation, 3 min post extubation, 4 min post extubation, 5 min post extubation

Secondary

MeasureTime frame
1. Extubation Time 2. Hemodynamic Parameters 3. Surgeon satisfaction 4. Adverse EffectsTimepoint: 1. During Extubation 2. 1 min post extubation 3. 2 min post extubation 4. 3 min post extubation 5. 4 min post extubation 6. 5 min post extubation

Countries

India

Contacts

Public ContactDR HARSHA

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES

drhussain72@yahoo.co.in9973152076

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026