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To compare the effect and haemodynamic stability associated with two intravenous drug combination -Ketamine and Dexmedetomidine with Propofol for total intravenous anaesthesia.

A cross-sectional study on comparing the effects of two techniques, Propofol Ketamine and Dexmedetomidine ketamine, in Total Intravenous Anaesthesia (TIVA) - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091419
Enrollment
100
Registered
2025-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group DK (Dexmedetomidine and Ketamine for TIVA: Group DK will receive a bolus dose of Inj. Dexmedetomidine 1micgmper kg BW and Inj.Ketamine 1mgper kg BW slow IV followed by Inj.Dexmede

Sponsors

Sree Balaji Medical College and Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Short duration surgical procedures that can be done under Total intravenous anaesthesia 2. Patients who are under ASA-Grade I and II without any Comorbid diseases in the age group between 20-50 years. 3. Patients who are willing to participate in this study

Exclusion criteria

Exclusion criteria: Pediatric and Geriatric age group patients Patients who gave a history of being allergic to this group of drugs Major surgical procedures that require complex anaesthetic or interventional techniques Refusal to participate in the study

Design outcomes

Primary

MeasureTime frame
To assess the quality of surgical anaesthesia induced by the combination of study drugs and the haemodynamic stabilityTimepoint: 1. Pre-operative baseline vital parameters Intraoperative vital parameters and duration of anaesthesia 0.5.10,15,30,45,60 minutes

Secondary

MeasureTime frame
Post-operative recovery score & post-operative duration of analgesia, & time for rescue analgesiaTimepoint: By using Ramsey sedation scoring & VAS scoring postoperatively at 0,15,30,45 minutes, & hourly till 6hours or the time for rescue analgesia -whichever is earlier

Countries

India

Contacts

Public ContactDr. Kala Balasubramanian

BIHER university

kalamhn@gmail.com9444680908

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026