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To compare the efficacy of myopia control spectacle lenses and low dose atropine eye drops as monotherapy and in combination in arresting the progression of near sightedness (myopic spectacle power) in Indian children.

Defocus Spectacles with 0.01 percent atropine eye drops for slowing myopia, a randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091396
Enrollment
52
Registered
2025-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H521- Myopia

Interventions

Intervention1: HALT spectacles: Stage 1: The patient after fulfilling the inclusion criteria is recruited One of his/her eyes will be randomized using block randomization of block size 6 To receive c

Sponsors

Dr Rimsha Parvez
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Magnitude of myopia ranging from -1d to -8d ser in each eye. Astigmatism less than -4d in each eye. Documented progressive myopia with an increase of more than or equal to 0.5d ser in each eye in the previous year. Children whose parents or guardian are willing to give a written informed consent.

Exclusion criteria

Exclusion criteria: Children with any ocular or systemic co-morbidities. Children with history of frequent eye rubbing. Children who have best corrected visual acuity of less than or equal to 6 by 12 on Snellens chart. Children having an inter-acuity difference of more than or equal to 2 lines on Snellens chart. Myopia progression in the last year of less than -0.5d ser in either eye.

Design outcomes

Primary

MeasureTime frame
Spherical Equivalent RefractionTimepoint: 4 months

Secondary

MeasureTime frame
Axial lengthTimepoint: 4 months

Countries

India

Contacts

Public ContactDr Mihir Kothari

Jupiter Hospital

drmihirkothari@gmail.com9324037173

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026