Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of OSMF and Oral Squamous cell carcinoma in the Age range of 25 45 years old individuals 2.Individuals of both the genders will be included 3.Individuals with history of smokeless Tobacco arecanut chewers will be included 4.Normal individuals who do not have any tobacco and areca nut habit history 5.Clinically diagnosed cases of OSMF based on clinical staging and mouth opening1. 6.Clinically diagnosed and histopathologically confirmed cases of OSCC
Exclusion criteria
Exclusion criteria: 1.Patients undergoing treatment for OSMF and OSCC. 2.Individuals with smoking history 3.Individuals with systemic illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identifying candidate biomarkers in saliva for early diagnosis, evaluate the progression, predict malignant transformation in OSMF and early diagnosis of Oral cancer which can help develop non invasive and rapid point of care tool for routine screening of these patients. This has public health implication in screening and early diagnosis of oral cancer . It will also help in stratifying the patients as per the disease progression and implement personalized treatment strategies. Timepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Department of Oral Pathology and Microbiology, KLE VK Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belgaum