Health Condition 1: 1- Obstetrics Health Condition 2: O80- Encounter for full-term uncomplicated delivery
Conditions
Interventions
Intervention1: Norepinephrine infusion: Norepinephrine infusion will be started immediately after spinal anaesthesia and infusion rates will be titrated based on maternal systolic blood pressure
Contr
Sponsors
University College of Medical Sciences and Guru Teg Bahadur Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Consenting healthy mothers with term, uncomplicated, singleton pregnancy scheduled to undergo elective caesarean section under spinal anaesthesia
Exclusion criteria
Exclusion criteria: History suggestive of maternal complications e.g., pre-eclampsia, cardiovascular disease, cerebrovascular disease Known risk factors for postpartum haemorrhage e.g., multiple gestation, abnormal placentation, uterine fibroid, macrosomia, hydramnios, history of postpartum haemorrhage or uterine atony Patients on monoamine oxidase inhibitors or tricyclic antidepressants History suggestive of presence of mesenteric or peripheral vascular thrombosis Patients with absolute or relative contra-indications for spinal anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total oxytocin dose requirementTimepoint: Intraoperative and 24 hours postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Adequacy of uterine tone Additional uterotonics used Estimated blood loss Fall in haemoglobin Side effects of vasopressors and oxytocin Incidence of postpartum haemorrhage Timepoint: Intraoperative and 24 hours postoperative | — |
Countries
India
Contacts
Public ContactDr Surbhi
University College of Medical Sciences and Guru Teg Bahadur Hospital
Outcome results
None listed