Health Condition 1: A419- Sepsis, unspecified organism
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
Dr Ruchi Gupta
Eligibility
Inclusion criteria
Inclusion criteria: Patients more than 16 and less than 85 years of age admitted with SIRS in intensive care unit will be included within 24 hours of admission. Sepsis will be defined based on Sepsis 3.0 definition and either clinically, radiologically or microbiological evidence of bacterial infection. Non infective SIRS will be defined by Acute pancreatitis or trauma presenting within 48hrs of onset.
Exclusion criteria
Exclusion criteria: 1.Refusal to give consent 2.Patients on Lipid lowering drugs 3.Severe Malnourishment: BMI less than18 or more than30 4.Uncontrolled diabetes mellitus (HBA1c more than 8) Known eating disorders. Known Metabolic Syndromes Post operative patients Non specific causes of SIRS Non bacterial causes of infection like viral, fungal protozoal etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the lipid profile in patients with sepsis and non-infective Systemic inflammatory response syndrome patients like acute pancreatitis and early trauma.Timepoint: Day 0 and 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the correlation between lipid profiles and 30-day mortality in patients with sepsisTimepoint: Day 0 and 3;To assess the association of the lipid profile in sepsis with severity of illness using APACHE II and Sequential Organ Failure Assessment (SOFA) score.Timepoint: day 0 and 3;To find the trend of the lipid profile over time (at admission and the 3rd day) in patients with sepsis admitted to the ICU.Timepoint: Day 0 and 3 | — |
Countries
India
Contacts
Public ContactDr Sumit Ray
Holy Family Hospital
Outcome results
None listed