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Studying how Methylene blue and Plain Lignocaine help reduce pain after Fistula surgery.

Observational analysis of analgesic effect of combination - Methylene Blue and Plain Lignocaine on postoperative pain following fistula in ano surgeries - N/A

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/091224
Enrollment
90
Registered
2025-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

KMC, Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age: Patients aged above 18 years. 2. Diagnosis: Clinically and/or radiologically confirmed anal fistula requiring surgical procedure for Fistula in Ano. 3. Surgical Procedure: Patients undergoing a surgical procedure for Fistula in Ano. 4. Pain Assessment Compliance: Patients who can reliably report postoperative pain using a standardized pain scale (e.g., VAS). 5. Patients with less than or equal to three external openings or wounds 6. Patients with diameter of external opening or wound of less than or equal to 5 cm.

Exclusion criteria

Exclusion criteria: 1. Age Restriction: Patients below 18 years. 2. Pre-existing Chronic Pain Disorders: Patients with chronic pain conditions or on long-term analgesic therapy (e.g., opioids, neuropathic pain medications). 3. Allergy or Hypersensitivity: Known hypersensitivity to methylene blue, local anaesthetics. 4. Pregnant or Lactating Women: Due to potential risks associated with methylene blue and analgesic agents. 5. Patients who do not provide consent or are unable to give consent. 6. Patients undergoing Seton placement procedure. 7. Patients with more than 3 external openings or wounds and patients with diameter of external opening/ wound more than 5 cm.

Design outcomes

Primary

MeasureTime frame
To evaluate the difference in pain scores (Visual Analogue scale) at postoperative day 1, 2, 3 between the two groups.Timepoint: Postoperative day 1, 2, 3—

Secondary

MeasureTime frame
To analyze the duration of hospital stay and its correlation with postoperative pain control in both groups as a parameter to understand change in standard of life.Timepoint: ;To assess the need of IV Analgesia in patients receiving Injection Methylene Blue.Timepoint: Postoperative day 1, 2, 3—

Countries

India

Contacts

Public ContactDr Steffi Jennifer Dcruz

Kasturba Medical College and Hospital

badareesh.l@manipal.edu8861038876

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026