FindTrial
Sign In

This study compares two settings of the breathing machine, ASV and PSV, to help ICU patients breathe on their own. ASV adjusts support automatically based on the patients needs, while PSV provides pressure based support that is manually adjusted.

Comparison of Adaptive Support Ventilation and Pressure Support Ventilation for Weaning and Extubation Outcomes in Critically Ill Patients in an Indian ICU: A Prospective Randomized Study - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091125
Enrollment
100
Registered
2025-07-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Adaptive support ventilation: ASV is an intelligent ventilator mode that automatically adjusts the level of breathing support based on the patients lung condition and effort to promote

Sponsors

Christian Medical College Vellore Tamilnadu India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Mechanical ventilation for at least 24 hrs Patients with APACHE II score of 5 - 20

Exclusion criteria

Exclusion criteria: a) Mechanical ventilation for less than 24 hours (including self extubation or death). b) Patients with Coexisting severe Neurological/ Neuromuscular/Quadriplegia/Critical illness neuropathy/ Critical illness Myopathy/ Myasthenia gravis/ Guillain Barre syndrome or cardiac diseases as it may prolong weaning for extra-pulmonary reasons. c) Pregnancy

Design outcomes

Primary

MeasureTime frame
Incidence of successful weaning Timepoint: 48 hrs after extubation—

Secondary

MeasureTime frame
1. Time to Successful Extubation, Duration from initiation of weaning to successful extubation. 2. Total Duration of Mechanical Ventilation, Time from intubation to final extubation 3. ICU Length of Stay, Total duration of ICU stay post initiation of weaning. 4. Mortality, ICU mortality rates. 5. Number of manual ventilator aadjustments & ABG sampling required in each group 6. VAP Incidence rate Timepoint: 1. baseline & 48hrs after extubation 2. at the time of extubation 3. at the time of discharge 4. at any point of the study after baseline. 5. at the time of extubation 6. at the time of extubation—

Countries

India

Contacts

Public ContactGeorge Prashanth Kurian

Christian medical college, Vellore

georgekurian14@gmail.com9655594316

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026