Comparison between two doses of oral paracetamol for reduction of pain on propofol injection during elective surgery.

Comparative evaluation of two different doses of oral paracetamol in alleviation of pain on Propofol injection in patients undergoing elective surgery under general anaesthesia. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/091097

Enrollment

Registered

2025-07-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Control Intervention1: Tablet Paracetamol 500mg Tablet Paracetamol 650mg: Patient will be randomly allocated and one of the two groups. The pain score is based on assessment of patients motor and ver

Eligibility

Inclusion criteria

Inclusion criteria: The study wil include 62 patients of either sex of age group 18-60 years, belonging to American Society of Anesthesiologists (ASA) physical status of 1-l posted for elective surgery under general anaesthesia of duration 1-3 hrs.

Exclusion criteria

Exclusion criteria: History of allergy to test drug, History of hepatic and renal dysfunction, History of psychological disorders, History of alcohol and drug abuse, Refusal to participate in the study will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
To compare and study of the effectiveness of two doses of oral paracetamol in alleviating the pain due to propofol injection.Timepoint: inj. propofol 2mgkg-1 given intravenously as total dose. After one fourth of the total dose has been given the assessing anaesthesiologist will use a specially designed composite pain scale described by Rochette and colleagues to evaluate the level of propofol injection pain.	—

Measure

Time frame

To compare and study of the effectiveness of two doses of oral paracetamol in alleviating the pain due to propofol injection.Timepoint: inj. propofol 2mgkg-1 given intravenously as total dose. After one fourth of the total dose has been given the assessing anaesthesiologist will use a specially designed composite pain scale described by Rochette and colleagues to evaluate the level of propofol injection pain.

—

Secondary

Measure	Time frame
To note side effects, if any.Timepoint: 24 hrs.	—

Countries

India

Contacts

Public ContactMD SALAUDDIN

Pt. B D Sharma, PGIMS, Rohtak

kadnandita@gail.com9896335544

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026