A study to see how preparing patients before surgery through cardiorespiratory fitness, nutrition, and mental support can help improve recovery and strength in people with colorectal cancer having planned surgery.

Prehabilitation augmented Enhanced Recovery After Surgery in patients undergoing elective surgery for colorectal carcinoma: a randomized control trial - PERAS(Prehabitation augmented Enhanced Recovery After Surgery)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/091096

Enrollment

Registered

2025-07-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C189- Malignant neoplasm of colon, unspecified

Interventions

Intervention1: High protein diet,Cardiorespiratory exercises,Psychological betterment,CAP.PREPROKEN,L-GLUTAMINE SACHET,SYP CAXFILA OS.: High protein diet acc to ideal body weight,Incentive spirometry,

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adults aged 18-90 years 2.Both gender 3.Biopsy proven colorectal carcinoma requiring surgical resection 4.Able to provide informed consent 5.ASA 1 or 2 patients

Exclusion criteria

Exclusion criteria: 1.Age less than 18yrs or more than 90yrs 2.Inability to comprehend or follow PERAS protocol 3.Patients not providing valid informed consent 4.Pregnant patients 5.Patients with psychiatric disorders 6.Patients presenting to emergency with obstruction or perforation in colorectal carcinomas

Design outcomes

Primary

Measure	Time frame
1)To compare the length of hospital stay, postoperative complications, and readmission rates between patients managed with Prehabilitation augumented ERAS and those receiving traditional ERAS care. 2)To assess patient-reported outcomes, such as pain scores, bowel function recovery, quality of life and emotional well being in the two groups. 3)To evaluate the cost-effectiveness of the Prehabilitation augumented ERAS protocol in comparison to traditional ERAS pathwaysTimepoint: Primary outcomes pertaining to this study specifically includes those which are used to determine the effects of intervention i,e, prehabilitation.Measures including borg scale,6MWT,hand grip test,improvement in pulmonary function test,duke activity index,change in BMI,PHQ9,GAD7 score etc will be assessed, 1.)At baseline, 2.)At 4 weeks, 3.)At 8 weeks, from the point of diagnosis/start of prehabilitative intervention.	—

Measure

Time frame

1)To compare the length of hospital stay, postoperative complications, and readmission rates between patients managed with Prehabilitation augumented ERAS and those receiving traditional ERAS care. 2)To assess patient-reported outcomes, such as pain scores, bowel function recovery, quality of life and emotional well being in the two groups. 3)To evaluate the cost-effectiveness of the Prehabilitation augumented ERAS protocol in comparison to traditional ERAS pathwaysTimepoint: Primary outcomes pertaining to this study specifically includes those which are used to determine the effects of intervention i,e, prehabilitation.Measures including borg scale,6MWT,hand grip test,improvement in pulmonary function test,duke activity index,change in BMI,PHQ9,GAD7 score etc will be assessed, 1.)At baseline, 2.)At 4 weeks, 3.)At 8 weeks, from the point of diagnosis/start of prehabilitative intervention.

—

Secondary

Measure	Time frame
1)To assess readmission rates within 30 days post surgery 2)To assess response to adjuvant chemotherapy & related complicationsTimepoint: Within 30 days of post operative period.	—

Countries

India

Contacts

Public ContactDr Satish S N

Postgraduate Institute of Medical Education and Research,Chandigarh

drsnsatish06@gmail.com9790674694

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026