Health Condition 1: D330- Benign neoplasm of brain, supratentorial
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with large supratentorial tumor of size more than 4cm in diameter on CT scan posted for craniotomy and excision. ASA grade 1-3
Exclusion criteria
Exclusion criteria: Ocular problems that could influence the ONSD or ETD, Optic nerve injury, Previous intracranial lesions/Craniotomy. Lumbar puncture performed within 2 weeks before study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure ONSD/ETD ratio using both the techniques and find their correlation with ICP value measured invasively.Timepoint: pre operative period and before induction ,intra operatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| -To find the correlation between ONSD/ETD ratio and neurological outcomes at 3 months (using Extended Glasgow Outcome Score (GOS-E)) -To compare the two techniques for their ability to predict the neurological outcomes at 3 months. - To monitor hemodynamic parameters (HR & MAP) in perioperative period - Brain Relaxation Score -Time to extubation -Length of hospital stay -Neurological status at the time of extubation & discharge. -Neurological outcome at the end of 3 months using Extended Glasgow Outcome Score (GOS-E). -Complications if any during perioperative period Timepoint: pre operative period , intra and post operative period .and at time of discharge and after 3 months | — |
Countries
India
Contacts
King Georges Medical University, Lucknow