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Measuring the thickness of optic nerve and eye ball size using USG AND CT scan using their correlation with pressure in the brain for predicting the neurological outcome

Evaluation of optic nerve sheath diameter to transverse diameter ratio for predicting the neurological outcome in patients undergoing supratentorial craniotomy: Comparison of USG AND CT Measurements - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091095
Enrollment
35
Registered
2025-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D330- Benign neoplasm of brain, supratentorial

Interventions

Intervention1: USG AND CT guided measurement of optic nerve sheath diameter and eyeball transverse diameter and measuring intracranial pressure.: Optic nerve sheath diameter and eyeball transverse di

Sponsors

KING GEORGE MEDICAL UNIVERSITY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with large supratentorial tumor of size more than 4cm in diameter on CT scan posted for craniotomy and excision. ASA grade 1-3

Exclusion criteria

Exclusion criteria: Ocular problems that could influence the ONSD or ETD, Optic nerve injury, Previous intracranial lesions/Craniotomy. Lumbar puncture performed within 2 weeks before study.

Design outcomes

Primary

MeasureTime frame
To measure ONSD/ETD ratio using both the techniques and find their correlation with ICP value measured invasively.Timepoint: pre operative period and before induction ,intra operatively.

Secondary

MeasureTime frame
-To find the correlation between ONSD/ETD ratio and neurological outcomes at 3 months (using Extended Glasgow Outcome Score (GOS-E)) -To compare the two techniques for their ability to predict the neurological outcomes at 3 months. - To monitor hemodynamic parameters (HR & MAP) in perioperative period - Brain Relaxation Score -Time to extubation -Length of hospital stay -Neurological status at the time of extubation & discharge. -Neurological outcome at the end of 3 months using Extended Glasgow Outcome Score (GOS-E). -Complications if any during perioperative period Timepoint: pre operative period , intra and post operative period .and at time of discharge and after 3 months

Countries

India

Contacts

Public ContactDR HEMLATA

King Georges Medical University, Lucknow

hema2211@yahoo.co.in9415410236

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026