Health Condition 1: - Health Condition 2: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Amoxicillin-Loaded Injectable Platelet-Rich Fibrin (i-PRF): 900 L of i-PRF will be mixed with 100 L of freshly prepared amoxicillin solution (stock concentration: 5 mg/mL) to achieve
Sponsors
Priyanka yadav
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient diagnosed with chronic periodontitis o Patients having periodontal pockets of more than 5 mm 2. Patient with clinical attachment loss more than 2 mm 3.Age group between 25- 50 years. 4. Patients with good general health, without any history of systemic disease or under medication 5. Patient ready to give written informed consent.
Exclusion criteria
Exclusion criteria: 1. Medically compromised patient. o Patient on antimicrobial therapy 2. Smokers and smokeless tobacco users. 3. Patients showing unacceptable oral hygiene during evaluation. 4. Patient who received periodontal therapy in the past 6 months. 5.Pregnant women and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of amoxicillin incorporated I-PRF as local drug delivery for the treatment.Timepoint: At base line, 1month, 3month | — |
Secondary
| Measure | Time frame |
|---|---|
| I.Assessment of gingival index and plaque index before and after placement of amoxicillin incorporated I-PRF as local drug delivery. II.Assessment of periodontal pocket depth (PPD) and clinical attachment index (CAL) before and after index before and after placement of amoxicillin incorporate I-PRF . III.To compare the effect of amoxicillin incorporated I-PRF with I-PRF alone as Local drug Delivery. Timepoint: At base line,1week,3week, 1month, 3month | — |
Countries
India
Contacts
Public ContactPriyanka Yadav
faculty of dental sciences IMS, BHU
Outcome results
None listed