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Using light-activated turmeric and beetroot extract to reduce infection in decayed teeth A comparison study

Comparative evaluation of antimicrobial effectiveness of photodynamic therapy using curcumin and beta vulgaris extract in teeth with periapical pathology :An in vivo study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090981
Enrollment
20
Registered
2025-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: curcumin and beta vulgaris: Intervention Group 1: Application of Curcumin solution followed by light activation as PDT in root canal. Intervention Group 2: Application of Beta vulgaris

Sponsors

URMY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients Single rooted teeth with pulp necrosis and radiographic size of peri apical lesion of diameter 2 to 5 mm. Potential to achieve canal patency The candidates ability to understand and provide informed consent

Exclusion criteria

Exclusion criteria: Teeth with incomplete formation of roots Radiographic size of periapical lesion of diameter geater than 5 mm Presence of resorption or obliterated root canals and root fractures Periodontal pockets deeper than 3 mm that is teeth with poor prognosis or any recent history of trauma. Those teeth from patients who had reported the use of anti inflammatory antibiotics and or immunosuppressive medications within the preceding 14 days for antibiotics and 3 to 5 days for antiinflammatory drugs or any systemic disease were not included in the study.

Design outcomes

Primary

MeasureTime frame
Reduction in microbial load in root canal samples following photodynamic therapy with Curcumin and Beta vulgaris extractTimepoint: AFTER 48 HOURS

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Chetan R Patil

Maratha Mandal Nathajirao G Halgekar Institute of Dental Sciences and Research centre

drchetanpatil81@gmail.com9448571310

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026