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Study Comparing a palnt based Gel and standard Gel for Treatment of Patients with Gum Disease

Comparative Evaluation of Resveratrol Gel and Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in the Treatment of Periodontitis: Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090908
Enrollment
40
Registered
2025-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Resveratrol gel: resveratrol a natural compound found in grape skins, peanuts, and berries, emerges as a promising candidate due to its dual anti-inflammatory and antioxidative propert

Sponsors

Jss dental college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with pocket depth equal to 5 to 6mm and or clinical attachment loss more than or equal to 4mm and angular bone loss more than or equal to 3 mm on intraoral periapical radiographs with no history of periodontal therapy or 6 months were included. One site per patient will be evaluated in maxilla or mandible to justify interpatient variation in clinical parameters, patient compliance and response to the drug administered.

Exclusion criteria

Exclusion criteria: 1. Patients with a known systemic disease; 2. Known or suspected allergy 3. with aggressive periodontitis; 4. who used tobacco in any form; 5. immunocompromised patients 6. Women suffering from breast, ovary and uterine cancer

Design outcomes

Primary

MeasureTime frame
To formulate and evaluate the efficacy of Resveratrol gel as a local drug delivery system as an adjunct to scaling and root planning for treatment of periodontitis.Timepoint: Data collection august 2025 to february 2026 first vist - scaling and root planing , application of gel , measurement of baseline data second visit - 1 week after removal of periodontal pack and checking oral hygiene maintenece third visit after 3 months for immunological evaluation fourth visit after 6 months for follow up and radiographic parameters

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Suman basavaraju

Jss dental college and hospital

sumanbv_72@yahoo.co.in9945551564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026