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Effect of probiotic intervention and oral mucosal changes in Tobacco chewers

Assessing the effect of Probiotic on Oral Mucosal Cytomorphometry and Candida Species Colonisation in Habitual Tobacco Chewers: An Experimental Study - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090877
Enrollment
126
Registered
2025-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Probiotics: Probiotics will be administered for a duration of 3 weeks. Control Intervention1: Nil: Single arm trial

Sponsors

Dr Deepa Jose
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants age ranging from 18-40 years History of use of commercial tobacco products for a minimum of 6 months

Exclusion criteria

Exclusion criteria: Participants who had undergone any type of treatment for tobacco lesions Participant with any oral potentially malignant or malignant lesion Participants with any systemic illness Recent history of Antibiotics usage Participants with history of allergy to dairy products Immunocompromised patients

Design outcomes

Primary

MeasureTime frame
Alteration in candida species colonization and cytomorphometry in tobacco users after probiotic intervention.Timepoint: 2 weeks—

Secondary

MeasureTime frame
Clinical Well beingTimepoint: 4 weeks—

Countries

India

Contacts

Public ContactDeepa Jose

Mar Baselios Dental College

dr.deepajose00@gmail.com9747593249

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026