Probiotics vs Synbiotics for Healthy Gums and Teeth in Kids with Dental Appliances

COMPARATIVE EVALUATION OF PROBIOTICS AND SYNBIOTICS ON PLAQUE ACCUMULATION, GINGIVAL HEALTH AND STREPTOCOCCUS MUTANS LEVELS IN CHILDREN WITH SPACE MAINTAINERS A RANDOMIZED CONTROLLED TRIAL - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090869

Enrollment

Registered

2025-07-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Probiotic sachet: children will Receive probiotic schets and will be instructed to take one sachet twice daily for 1 month Intervention2: Synbiotic Sachets: will Receive Synbiotic sche

Eligibility

Inclusion criteria

Inclusion criteria: 1.Children aged 6-12 years 2. Patients with space maintainers 3. Good general health 4. Willingness to participate and comply with the study protocol 5. Patients who have not taken antibiotics or antifungal medications within the past 3 months

Exclusion criteria

Exclusion criteria: 1. Patients with a history of allergies to probiotics or synbiotics. 2. Patients with a compromised immune system. 3. Patients with any systemic disease that may affect oral health.

Design outcomes

Primary

Measure	Time frame
There is a significant difference in the effectiveness of Synbiotics and Probiotics on plaque accumulation, gingival health and Streptococcus mutans count and in children with space maintainers.Timepoint: There is a significant difference in the effectiveness of Synbiotics and Probiotics on plaque accumulation, gingival health and Streptococcus mutans count and in children with space maintainers.	—

Secondary

Measure	Time frame
There is no significant difference in the effectiveness of Synbiotics and Probiotics on plaque accumulation, gingival health and Streptococcus mutans counts in children with space maintainers.Timepoint: 1 year	—

Countries

India

Contacts

Public ContactSHIVANGI SHIVSAMB SWAMI

Maharashtra Institute of Dental Sciences and Research Dental College Maharashtra

shivangisswami@gmail.com09373351274

Outcome results