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A Study Comparing Calcium Hydroxide, Bio-C Repair, and Calcimol-LC for Treating Deep Cavities in Lower First Molars

Comparative Evaluation of Treatment Outcomes Of Indirect Pulp Capping Using Calcium Hydroxide, Bio-C Repair, And Calcimol-LC In Permanent Mandibular First Molars With Deep Carious Lesion: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090864
Enrollment
75
Registered
2025-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: calcium hydraoxide: 1. Calcium hydroxide is widely used in indirect pulp capping due to its excellent antibacterial properties. 2. It promotes the formation of tertiary dentin by stimu

Sponsors

Dr Diksha kumari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between eighteen to forty years. Presence of deep carious lesions without pulp exposure, with radiographic depth reaching three-fourths of the dentin. Positive response to pulp sensibility tests, including Electric Pulp Test and cold test. No history of spontaneous pain. No evidence of periodontal ligament space widening. Permanent molars with adequate coronal tooth structure suitable for restoration.

Exclusion criteria

Exclusion criteria: Presence of periapical pathology such as periapical radiolucency or root resorption. Extensive loss of coronal tooth structure requiring prosthetic rehabilitation. Presence of caries extending below the gingival margin. History of chronic or recurrent pain associated with the affected tooth. Presence of soft tissue swelling or sinus tract. Teeth with open apices or pathological mobility. Teeth that have been previously treated endodontically or restored in the area under study. Patients with known systemic health complications.

Design outcomes

Primary

MeasureTime frame
Check pulpal response using EPT/Cold Test at intervals of 1 week, 3 months and 6 months post-procedure.Timepoint: Check pulpal response using EPT/Cold Test at intervals of 1 week, 3 months and 6 months post-procedure.

Secondary

MeasureTime frame
Clinical symptoms & comparative success ratesTimepoint: 1st week 3 month & 6 month

Countries

India

Contacts

Public ContactDr Vijay kumar

Himachal Dental College, Sundernagar,

drvk9900@rediffmail.com7650000300

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026