Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Different doses of intravenous Dexmeditomidine infusion in attenuating haemodynamic responses to pneumoperitoneum and post Operative recovery in patients undergoing laparoscopic surgeri
Sponsors
Chaithra V P
Eligibility
Inclusion criteria
Inclusion criteria: All ASA grade 1 and 2 patients with BMI more than 18.5kg per meter square and less than 28kg per metre square, posted for elective laparoscopic surgery under general anaesthetia.
Exclusion criteria
Exclusion criteria: Patients with ischemic heart disease, uncontrolled diabetes mellitus, asthma, COPD, uncontrolled hypertension,chronic renal disease and liver diseases. Pregnant woman or lactating woman. Patients with anticipated difficulty airway. Patients with ASA grade 3 or more.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in haemodynamic parameters- Heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure at intubation, during pneumoperitoneum and at extubation. Cough reflex, shivering and sedation score post operatively.Timepoint: Changes in haemodynamic parameters- HR,SBP,DBPand MAP at baseline,at the end of Dexmeditomidine infusion,1 and 5 min after intubation,before creating pneumoperitoneum,5,15,30,45,60,90 min after creating pneumoperitoneum, at the end of pneumoperitoneum and before extubation, after extubation, 5 min and 20 min after extubation. Cough reflex, shivering and sedation score at extubation,20 min,2 hrs and 6hrs after extubation post operatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score and first rescue analgesia post operatively. Adverse effects like Hypotension, bradycardia, PONV.Timepoint: First rescue analgesia after completion of surgery VAS more than 4 Hypotension, bradycardia, PONV at extubation, 20min, 2hr and 6hr. | — |
Countries
India
Contacts
Public ContactKokila N
Mysore medical college and Research institute.
Outcome results
None listed