Health Condition 1: 3- Administration
Conditions
Interventions
Intervention1: Inj. Nalbuphine 0.5 mg: Intrathecal injection of 0.5 mg Nalbuphine as an adjuvant to 0.75% hyperbaric Ropivacaine.Patients will be observed postoperatively for 6 hours to assess duratio
Sponsors
Bangalore Medical College and Research Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA physical status I and II 2. Patients aged 18 to 65 years 3. Elective lower limb surgeries under spinal anaesthesia 4. Written informed consent obtained
Exclusion criteria
Exclusion criteria: 1.Allergy to study drugs 2. Coagulopathy or anticoagulant therapy 3. Severe hepatic or renal or cardiac diseases 4. Local infection at injection site 5. Neurological deficits or spine deformities 6. Pregnancy or lactation 7. Refusal to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of effective analgesia (time from intrathecal injection to first request for rescue analgesia)Timepoint: At time of first request for rescue analgesia, up to 6 hours post intrathecal injection | — |
Secondary
| Measure | Time frame |
|---|---|
| Onset of sensory blockadeTimepoint: From intrathecal injection to loss of pinprick sensation at T12 dermatome ;Onset and duration of motor blockadeTimepoint: Time to achieve Bromage score 3 and duration until return to score 0 | — |
Countries
India
Contacts
Public ContactDr Saima Z
Bangalore Medical College and Research Institute
Outcome results
None listed