Skip to content

Comparing pain after root canal treatment using two different methods with and without painkillers: A Clinical Study

Evaluation of post operative pain following the use of two different file systems with two different cross- sectional designs with and without the use of preoperative analgesics: A Randomized Clinical Trial - nil

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090779
Enrollment
48
Registered
2025-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Protaper gold file system, Zerodol SP: Group 1- protaper gold file system with preoperative zerodol SP given one hour before the procedure, Group 2- protaper gold file system without p

Sponsors

Sonia S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: single rooted teeth with symptomatic irreversible pulpits, absence of periodical changes, ASA-1 category patients, patients who have not taken anti-depressants, analgesics or sedative drugs in the past 12 hours before treatment, patient who understand visual analog scale, patient willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Multi rooted teeth or teeth with periapical changes, breastfeeding or pregnant women, patient allergic to anaesthetics or NSAIDS, use of immunosuppressants, patients who have taken analgesics, anti depressants or sedative drugs in the past 12 hours, calcified and resorbed canals, complex canal anatomy, non vital pulp, unrestorable teeth, teeth with acute and chronic apical abscess, teeth with previous endodontic treatment, patient with systemic infections.

Design outcomes

Primary

MeasureTime frame
To determine the intensity of postoperative pain using visual analog scaleTimepoint: baseline before treatment, 6 hours, 12 hours, 18 hours, 24 hours, 48 hours and 72 hours

Secondary

MeasureTime frame
monitor analgesic consumption -number & frequency postoperatively, monitor patient comfort, Record procedural error- file separation, canal transportationTimepoint: 6 hours, 12 hours, 18 hours, 24 hours, 48 hours & 72 hours

Countries

India

Contacts

Public ContactSonia S

Tagore dental college and hospital

sriramorthodental@gmail.com9841074234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026