Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
Intervention1: Individualized homoeopathic medicines: 1-2 globule/s of indicated medicine in LM potency is to be dissolved in 120 ml of dist. water. Add 10 drops of rectified spirit and give 10 downwa
Sponsors
Central Council for Research in Homoeopathy
Eligibility
Inclusion criteria
Inclusion criteria: Participants of either sex aged between 20 and 60 years Participants diagnosed with elevated BP between 120 and 129 or less than 80 mm Hg or Stage 1 hypertension with systolic BP between 130 and 139 mm Hg or diastolic between 80 and 89 mm Hg as per the American College of Cardiology or American Heart Association 2017 Willing and able to participate for 3 months
Exclusion criteria
Exclusion criteria: Participants who are already on hypertensive medications. Participants who have a history of Cardiac Arrhythmia, Acute Coronary Syndrome, Myocardial Infarction, congestive cardiac failure, Stroke, or Severe Arrhythmia in the last 6 months. Participants with Stage-2 hypertension greater than or equal to 140 mm Hg systolic or greater than or equal to 90 mm Hg diastolic, as per the American College of Cardiology or American Heart Association 2017. Participants with concurrent Hepatic Dysfunction defined as AST and or ALT greater than 2 times the upper standard limit or Renal Dysfunction defined as S. creatinine greater than 1.2mgdl, uncontrolled diabetes mellitus HbA1C greater than 8, uncontrolled Pulmonary Dysfunction asthmatic and COPD patients, or significant systemic illness necessitating long term drug treatment Rheumatoid arthritis, Neurological disorders, Endocrinal disorders, etc.) or Known cases of malignancy. Women who are planning for conception or pregnancy or lactating. Participants with history of hypersensitivity to homeopathic medicines or any doses form. Participants taking homoeopathic medicines for any other diseases in the last 2 weeks. Any other condition that the PI thinks may jeopardize the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: 1.Changes from baseline systolic and diastolic blood pressure measurements. 2.Changes in the serum level of HLDF 24 peptide, TNF superfamily 14 (LIGHT), Amyloid-A, Homocysteine, Interleukin -6, and CRP. Timepoint: Changes from baseline systolic and diastolic blood pressure measurements. [Time frame: During every follow-up of 15 days for the period of 12 months] Changes in the serum level of HLDF 24 peptide, TNF superfamily 14 (LIGHT), Amyloid-A, Homocysteine, Interleukin -6, and CRP. [Time frame: Baseline, 3 months, 6 months, 9 months and 12 months] | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the SF-36-Health Survey Score. Changes in the level of serum cholesterol, triglyceride, and HbA1C. Change in the ORIDL Score. Timepoint: Change in the SF-36-Health Survey Score. [Time frame: Monthly for 12 months.] Changes in the level of serum cholesterol, triglyceride, and HbA1C [Time frame: Baseline, 3 months, 6 months, 9 months and 12 months] Change in the ORIDL Score. [Time frame: During every follow-up of 15 days for the period of 12 months] | — |
Countries
India
Contacts
Public ContactDr Pankhuri Misra
Dr.D.P. Rastogi Central Research Institute for Homoeopathy
Outcome results
None listed