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Comparative study between liposomal curcumin versus autologous exosomes after extraction of 3rd molar

Comparative evaluation of systemic use of liposomal curcumin versus autologous exosomes in healing of fresh extraction socket- A randomize controlled study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090745
Enrollment
60
Registered
2025-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Exosomes: 3rd molar surgery Control Intervention1: Liposomal curcumin: Liposomal curcumin after extraction of 3rd molar

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 50 years Medically healthy Indicated for non infected, single tooth extraction Non smokers or light smokers less than five cigarettes per day Willing to provide written informed consent and comply with follow up schedule

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Soft tissue healing assessed using Landry, Turnbull & Howley Healing Index at Day 7, Week 4, and Week 8Timepoint: Duration of study- 3 months—

Secondary

MeasureTime frame
Postoperative pain using Visual Analog Scale (VAS) Radiographic bone healing assessed via IOPA or CBCT at 4 & 8 weeks Timepoint: Week4 ,week8—

Countries

India

Contacts

Public ContactJyoti kumari

Professor Department of oral surgery, Manav Rachna international institute of research and science

nitinbhagat.sds@mrei.ac.in9953784571

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026