Health Condition 1: F112- Opioid dependence
Conditions
Interventions
Intervention1: Yoga Therapy and Treatment as usual: Yoga module for Substance use
disorder during Acute
withdrawal phase and Maintenance phase is given along with treatment as usual for the interventi
BART -Balloon Analogue Risk Task
YPA Yoga performance assessment
Work and Social Adjustment Scale (WSAS), symptoms
severity with COWS(Clinical opiate withdrawal scale).
Control Intervention1: Treatment as usual and Interactive Health Education with stretching exerc
Work and Social Adjustment Scale (WSAS), symptoms severity with COWS(Clinical opiate withdrawal scale).
Sponsors
Department of Integrative Medicine NIMHANS
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of Opioid use disorder. Subjects with mild to moderate severity of withdrawal symptoms (Clinical Opiate Withdrawal Scale: COWS score below 24). Subjects who got admitted into CAM, NIMHANS, and started treatment with Buprenorphine. Age range: 18 to 45 years. Both genders. Written informed consent.
Exclusion criteria
Exclusion criteria: COWS score more than 25. Patients not willing to give informed consent. History of current medical illness that may significantly affect brain functions. Patients with intractable pain due to other diseases and those on prescribed opioids for the pain of other medical conditions. Impaired general intellectual functioning (Mini-Mental Status Exam, MMSE below 24). Past history of head injury or concomitant severe medical conditions. With co-morbid (alcohol/benzodiazepine/cannabis or multiple) substance dependence except nicotine. Subjects who had received specific yoga practices for OUD in the past. Pregnant or post-partum subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stop signal task. Number and Frequency of Relapsing episodes.Timepoint: Baseline, 3 months, 6 months and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Opiate Withdrawal Scale (COWS) Digit Span Test (DST) - Forward and Backward Corsi span test (CST) Trail Making Test (TMT) Wisconsin Card Sorting Test (WCST) Balloon Analogue Risk Task (BART) Stop signal task with fMRITimepoint: Baseline, 3 months and 6 months | — |
Countries
India
Contacts
Public ContactDr Bharath Holla
National Institute of Mental Health and Neuroscience.
Outcome results
None listed