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Measuring saliva levels of YKL-40 and LL-37 in children with Down syndrome: A study of 8 - 15 years old.

Evaluation of YKL-40 and LL-37 levels in saliva of children with Down syndrome: A cross sectional study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/090686
Enrollment
60
Registered
2025-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q909- Down syndrome, unspecified

Interventions

Intervention1: nil: nil Intervention2: YKL-40 and LL-37 biomarker.: Comparing the levels of YKL-40 and LL-37 levels in the saliva of healthy and Down syndrome patients.

Sponsors

Dr Prapti Subhash Gayakwad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children with Down Syndrome in the age group of 8 to 15years. 2. Cooperative children based on Frankel behaviour rating scale 3 and 4

Exclusion criteria

Exclusion criteria: 1. Children on long term medication 2. Down syndromic children who were extremely uncooperative 3. Children if they had taken antibiotics or anti inflammatory drugs 4. Children with severs intellectual disability and or cardiac condition present along with Down Syndrome.

Design outcomes

Primary

MeasureTime frame
8 weeksTimepoint: base line—

Secondary

MeasureTime frame
Inflammatory biomarker levels will be higher in Down syndrome patients.Timepoint: One year—

Countries

India

Contacts

Public ContactDr Prapti Subhash Gayakwad

The Oxford Dental College Bangalore

sudhannks@gmail.com9886035137

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026