Efficacy of Surgical intervention over Percutaneous drainage in Infected Pancreatic Necrosis

Efficacy of Video-Assisted Retroperitoneal Debridement (VARD) Over Radiological Percutaneous Interventions (RPI) in the Management of Infected Pancreatic Necrosis:An Open Labelled Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090669

Enrollment

Registered

2025-07-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K859- Acute pancreatitis, unspecified

Interventions

Intervention1: Video-Assisted Retroperitoneal Debridement: Video-Assisted Retroperitoneal Debridement is a minimally invasive procedure that provides direct access to the necrotic cavity through a ret

Eligibility

Inclusion criteria

Inclusion criteria: Patients of more than 18 years ago with Documented infected necrotizing pancreatitis for more than 14 days of disease onset and Catheter drainage of the collection with infected necrosis is technically feasible as deemed by the Expert Radiologist and/or treating physician

Exclusion criteria

Exclusion criteria: Conditions with Indication for emergency laparotomy for abdominal catastrophe (e.g. bleeding, bowel perforation, abdominal compartment syndrome),or Previous retroperitoneal intervention for necrotizing pancreatitis or Documented chronic pancreatitis

Design outcomes

Primary

Measure	Time frame
To assess the efficacy of Video assisted retroperitoneal debridement compared to radiological percutaneous interventions in patients with suspected infected pancreatic necrosis.Timepoint: 1 year	—

Secondary

Measure	Time frame
To estimate the proportion of different outcomes among patients undergoing VARD and RPI in terms of Mortality, New onset (multi) organ failure, Bleeding requiring intervention, Perforation requiring intervention, Fistula formation,Incisional hernia, Wound infections, Endocrine and exocrine pancreas insufficiency, Number of patients with severe complications (Clavien-Dindo III or higher), Number of patients per Clavien-Dindo classification, Number of (re-)interventions, hospital and ICU length of stay, Direct costs. Timepoint: 1 year	—

Measure

Time frame

To estimate the proportion of different outcomes among patients undergoing VARD and RPI in terms of Mortality, New onset (multi) organ failure, Bleeding requiring intervention, Perforation requiring intervention, Fistula formation,Incisional hernia, Wound infections, Endocrine and exocrine pancreas insufficiency, Number of patients with severe complications (Clavien-Dindo III or higher), Number of patients per Clavien-Dindo classification, Number of (re-)interventions, hospital and ICU length of stay, Direct costs. Timepoint: 1 year

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Countries

India

Contacts

Public ContactDrUtpal Anand

AIIMS Patna

utpalanand2@gmail.com9661507725

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026