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Comparison between Pretreatment with low dose Ketamine and low dose Propofol for reducing Jerky muscle movement caused by Etomidate as an induction agent.

A Comparative Study between low dose Ketamine and low dose Propofol for the reduction of myoclonus caused by Etomidate as an induction agent. - NILL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090650
Enrollment
99
Registered
2025-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pretreatment with low dose Ketamine 1 minute before induction with Etomidate: Low dose Ketamine at 0.2 mg/kg IV administered 1 minute before induction with IV Etomidate (0.3 mg/kg) and

Sponsors

SADHARIYA MONA DIPAKBHAI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients Scheduled For Elective Surgeries Requiring General Anaesthesia with ASA I and II

Exclusion criteria

Exclusion criteria: Known Allergy or Contraindication to Ketamine , Propofol and Etomidate or History of Epilepsy or other Seizure Disorders or Pregnant or Breast Feeding women or ASA III , IV and V or Patients on chronic sedative or analgesic medication

Design outcomes

Primary

MeasureTime frame
Incidence and Severity of Myoclonus following Etomidate administrationTimepoint: Baseline, 1 min,2 min ,3 min ,5 min ,10 min, 15 min, 30 min ,45 min ,1 hr, 1hr 30 min , 2 hr,Post op Immediate,Post op 1 hr—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactCHIRAG PATEL

BJ MEDICAL COLLEGE AHMEDABAD

drchiragpateld10@gmail.com9898126456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026