Skip to content

To evaluate the effect of chitosan for treatment of deep dental carious lesion involving pulp

Effectiveness of chitosan in vital pulp therapy of carious exposed permanent teeth- a randomized control trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090641
Enrollment
66
Registered
2025-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Chitosan: Chitosan (C6H11NO4)n is a natural biopolymer made from chitin, which is found in the shells of crustaceans. Chitosan is a white, odorless, and biodegradable substance that has

Sponsors

Dr Ritwik Bainsla
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pulp sensibility testing i.e. thermal or electrical test showing vital pulp. Teeth with negative or mild tender on percussion and the mobility within normal limits. Pre-operative signs and symptoms of reversible pulpitis or symptomatic irreversible pulpitis. No periapical pathology on radiographic assessment. The teeth should be restorable with any permanent restoration immediately.

Exclusion criteria

Exclusion criteria: Patients with general contraindications to dental treatment Teeth with completed Root canal treatment or Vital pulp therapy Teeth associated with swelling, abscess, fistula, or abnormal mobility Teeth with external or internal resorption, prominent radiolucency at the periapical regions or furcation or calcification. Teeth with cracks, periodontitis or tooth fracture Teeth not responsive to pulp sensibility test

Design outcomes

Primary

MeasureTime frame
Patient responses like subjective and objective signs and symptoms. Pulp sensibility testing like thermal or electricalTimepoint: one three and six months

Secondary

MeasureTime frame
Intraoral periapical radiographs to rule out development of any periapical pathology and to evaluate for any evidence of formation of dentinal bridgeTimepoint: six and nine months

Countries

India

Contacts

Public ContactDr Shikha Jaiswal

Subharti Dental College and Hospital

shikhajais18@yahoo.com9760707057

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026