Study Comparing the Response of Intranasal and Nebulized Dexmedetomidine during Intubation

COMPARATIVE STUDY OF DEXMEDETOMIDINE INTRANASAL VS NEBULIZATION DEXMEDETOMIDINE EFFECT ON INTUBATION REPONSE - A PROSPECTIVE RANDOMISED DOUBLE-BLIND STUDY - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090628

Enrollment

Registered

2025-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: COMPARATIVE STUDY OF DEXMEDETOMIDINE INTRANASAL VS NEBULIZATION DEXMEDETOMIDINE EFFECT ON INTUBATION REPONSE: 30 CASES OF NEBULISATION DEXMEDETOMIDINE (GROUP N) RECIEVE 1 mcg/kg WITH 5

Eligibility

Inclusion criteria

Inclusion criteria: A) ASA GRADE I & II PATIENTS B) AGE 18 YEARS 60 YEARS C) ELECTIVE SURGERIES UNDER GENERAL ANAESTHESIA

Exclusion criteria

Exclusion criteria: A) REFUSAL OF CONSENT B) KNOWN OR ANTICIPATED DIFFICULT AIRWAY C) EMERGENCY SURGERIES D) PREGNANT PATIENTS E) PATIENTS WITH HEART BLOCK F) PATIENTS ON BETA BLOCKERS G) PATIENTS HAVING BRADYCARDIA F) BMI MORE THAN 30 kg/m2

Design outcomes

Primary

Measure	Time frame
THE PRIMARY OUTCOME IS TO COMPARE THE EFFECT OF DEXMEDETOMIDINE NEBULISATION VS INTRANASAL DEXMEDETOMIDINE ON LARYNGOSCOPY AND INTUBATION RESPONSETimepoint: 120 MINUTES	—

Secondary

Measure	Time frame
THE SECONDARY OUTCOME IS TO EVALUATE SEDATION SCORE FOR DEXMEDETOMIDINE NEBULISATION VS INTRANASAL DEXMEDETOMIDINE BEFORE INTUBATIONTimepoint: 120 MINUTES	—

Countries

India

Contacts

Public ContactDR ANAND S

CHETTINAD HEALTH AND RESEARCH INSTITUTE

dranandmurugan@gmail.com9444486183

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026