Is a shorter fast before endoscopy just as good as overnight fasting for patients requiring elective endoscopy in visualising the stomach lining during the endoscopy procedure?

Comparison of conventional overnight fasting with abbreviated fasting protocol regarding the mucosal visibility in patients undergoing esophagogastroduodenoscopy: a non-inferiority, randomised controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090627

Enrollment

124

Registered

2025-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K254- Chronic or unspecified gastric ulcer with hemorrhage Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Intervention Group: Nil per oral after midnight. Light breakfast (two idlis) 4 hours before the EGD (approximately 8 AM). Participants will also receive Metoclopramide 10 mg (to acceler

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants aged between 18 to 70 years. 2. Participants planned for elective, unsedated EGD. 3. Participants scheduled for EGD between 10 AM to 12 PM.

Exclusion criteria

Exclusion criteria: 1. Patients with suspected or known case of GI obstruction. 2. Already receiving prokinetic medications. 3. Known diabetic patients. 4. Patients scheduled for emergency or therapeutic EGD. 5. Pregnant or lactating females. 6. History of upper GI surgery. 7. Participants with known sensitivity or intolerance to metoclopramide. 8. Participants on antiepileptic drugs or medication for extrapyramidal disorders.

Design outcomes

Primary

Measure	Time frame
In patients undergoing elective esophagogastroudonoscopy, following conventional overnight fasting protocol and abbreviated fasting protocol, to evaluate and compare mucosal visibility during elective EGD, using the Total Visibility Score.Timepoint: In patients undergoing elective esophagogastroudonoscopy, following conventional overnight fasting protocol and abbreviated fasting protocol, to evaluate and compare mucosal visibility during elective EGD, using the Total Visibility Score. Which will be assessed during the procedure.	—

Measure

Time frame

In patients undergoing elective esophagogastroudonoscopy, following conventional overnight fasting protocol and abbreviated fasting protocol, to evaluate and compare mucosal visibility during elective EGD, using the Total Visibility Score.Timepoint: In patients undergoing elective esophagogastroudonoscopy, following conventional overnight fasting protocol and abbreviated fasting protocol, to evaluate and compare mucosal visibility during elective EGD, using the Total Visibility Score. Which will be assessed during the procedure.

—

Secondary

Measure	Time frame
a. The comfort of the patient, before and during EGD, will be assessed using the Visual Analogue Scale (VAS).Timepoint: before and after the procedure;b. The incidence of adverse events such as nausea, vomiting, aspiration, or hypoglycemia.Timepoint: Before and after the procedure;c. The percentage of patients requiring repeat EGD.Timepoint: after the procedure	—

Countries

India

Contacts

Public ContactReddy Abhinaya P

JIPMER

reddy.kmc2k6@gmail.com04132962633

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026