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Longitudinal study on dengue and Zika infections in Kerala

Profiling the clinico-epidemiological, genomic, and immunological markers of dengue and Zika infections and co-infections in Kerala, India via longitudinal studies - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/090539
Enrollment
28000
Registered
2025-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B978- Other viral agents as the cause ofdiseases classified elsewhere

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Wellcome Trust
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients meeting the WHO probable dengue case definition 2009 or the WHO suspected Zika case definition 2016 with symptom onset including fever within the past five days. Patients willing to provide informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Patients who is not willing to give informed written consent

Design outcomes

Primary

MeasureTime frame
immune correlates of primary and secondary dengue and zika infections and co-infectionsTimepoint: Day 1, 3 and 28 of onset of illness—

Secondary

MeasureTime frame
dengue & zika burden, clinical features, severity pattern, maternal & neonatal outcomes, genomics of virus, Aedes mosquito bionomics & infectionTimepoint: patients will be followed up on 3rd & 28th day of illness to assess the clinical outcomes. Vector studies will be done every month to capture seasonal variations—

Countries

India

Contacts

Public ContactDr Arya Rahul

Indian Council of Medical Research Vector Control Research Centre

drmanjurahi@gmail.com9999002837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026