Evaluation of 2 different mouthrinse on plaque induced gingivitis patient with fixed orthodontic appliances

Comparative evaluation of the Efficacy of mouthrinse containing 0.1% Hyaluronic Acid and 0.2% Chlorhexidine gluconate and mouthrinse containing 0.2% Chlorhexidine gluconate alone in plaque induced gingivitis patients with fixed orthodontic appliance: A Clinico- biochemical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090473

Enrollment

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: 0.1% hyaluronic acid and 0.2% Chlorhexidine gluconate: Efficacy of Mouthrinse containing 0.1% hyaluronic acid and 0.2% Chlorhexidine gluconate in plaque induced gingivitis patients with

Eligibility

Inclusion criteria

Inclusion criteria: Participants with full-mouth fixed orthodontic appliance with plaque-induced gingivitis Participants between age group of 18 years and above. Presence of at least 24 natural teeth in the mouth excluding the third molars Mild/moderate/severe gingivitis ( GI score by Loe & Silness 0.1-3.0) Probing depth not more than 3 mm

Exclusion criteria

Exclusion criteria: Physical or mental handicap. Syndromic / systemic diseases contributing to inflammatory process. Participants who had taken antibiotic therapy in the month prior to the commencement of the study. Participants with known allergy to chlorhexidine or Hyaluronic acid. Participants currently using mouthwashes Smoking Pregnant and lactating women. Active caries. Participants on anticoagulants

Design outcomes

Primary

Measure	Time frame
Reduction in plaque score and gingival index score ( gingival inflammation)Timepoint: Assessed at baseline , 15 th day and at 1 month	—

Secondary

Measure	Time frame
Changes in inflammatory biomarker levels in both the groupsTimepoint: Assessed at baseline and at 1 month from baseline	—

Countries

India

Contacts

Public ContactDr Rajesh K S

Yenepoya Dental College

rksdental@gmail.com9448529518

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026