Comparison between two different type of radiation treatment in patients with breast cancer treated with breast conservation surgery to observe survival outcome.

A prospective study to compare standard and modified hypofractionated adjuvant radiotherapy in patients with carinoma breast treated with breast conservation surgery. - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090468

Enrollment

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Modified hypofractionation: 34 gray in 10 fractions Control Intervention1: Standard hypofractionated radiotherapy: 40 gray in 15 fractions

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with carcinoma breast treated with breast conservation surgery and chemotherapy (neoadjuvant or adjuvant). 2.Patients wih adequate lung function,liver function,hematological parameters.

Exclusion criteria

Exclusion criteria: 1.Patient in whom radiation is a contraindication(Collagen vascular disease,Pregnancy) 2.Previous history of mediastinal radiation (within 5 yrs). 3.History of any other malignancy within past 5 years including breast cancer. 4.Any uncontrolled co-morbid condition.

Design outcomes

Primary

Measure	Time frame
Locoregional failure free survivalTimepoint: 3 monthly till 18 months	—

Secondary

Measure	Time frame
Toxicity as per CTC AE V 5Timepoint: 3 monthly till 18 months	—

Countries

India

Contacts

Public ContactDr Amitabha Manna

Institute of post graduate medical education & research

amitavamanna1965@gmail.com9433009577

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026