Ovulation induction in pcod patient by letrozle by comparing study

Letrozole stair-step protocol versus standard protocol of ovulation induction in patients with polycystic ovarian syndrome. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090454

Enrollment

108

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: NIL: letrozole efficacy and saftey in ovulation induction in PCOS patient Intervention2: Ovulation induction by letrozole: 2.5 to 7.5 mg od for 5 days each month for 6 months Interventi

Eligibility

Inclusion criteria

Inclusion criteria: All women giving written and informed consent. Women aged 21-40 years. Diagnosis of PCOS based on the Rotterdam criteria. History of anovulatory infertility Normal uterine and tubal patency confirmed by hysterosalpingography or laparoscopy. Normal semen analysis of partner according to WHO criteria

Exclusion criteria

Exclusion criteria: All women not giving written and informed consent. History of hypersensitivity to letrozole or similar drugs Liver or renal dysfunction Endocrine disorders other than PCOS (e.g., thyroid disease, hyperprolactinemia) Previous ovulation induction within the last 3 months Current or past history of breast or endometrial cancer

Design outcomes

Primary

Measure	Time frame
Ovulation induction Timepoint: 6 Months	—

Secondary

Measure	Time frame
Mean time of ovulation Pregnancy and live birth rate Multiple pregnancy rate Timepoint: 1 year	—

Countries

India

Contacts

Public ContactLAKSHMI KUMARI

CHAUDHARY CHARAN SINGH UNIVERSITY

lakshmikmri141@gmail.com7651850526

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026