A comparative study of epidural and local anaesthesia for inta-operative and post-operative pain management in patients undergoing transforaminal endoscopic discectomy.

Comparison of pain scores with epidural and local anaesthesia in patients undergoing transforaminal endoscopic discectomy - A prospective randomised trial. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090451

Enrollment

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M511- Thoracic, thoracolumbar and lumbosacral intervertebral disc disorders with radiculopathy

Interventions

Intervention1: Administration of epidural anaesthesia and local anaesthesia: Administration of epidural anaesthesia by 10ml of 0.2 percent Bupivacaine to one group of participants and local anaesthesi

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade 1 and 2 2. Patients undergoing single level lumbar discectomy 3. Typical symptoms of nerve compression not relieved with conservative management and epidural steroid injections

Exclusion criteria

Exclusion criteria: 1. Patients with sepsis 2. Patients with local site infection 3. Patients with allergy to local anaesthetics 4. Patients with coagulation abnormalities 5. Mentally unstable patients 6. Patients with hemodynamic instability 7. Severe systemic disease 8. Spinal abnormality

Design outcomes

Primary

Measure	Time frame
A prospective randomised clinical trial to compare the analgesic efficacy of epidural and local anaesthesia in patients undergoing transforaminal endoscopic discectomy.Timepoint: Assessment done at pre procedure, during sheath placement phase, during inter vertebral disc removal phase, at the end of procedure and 1 week post operatively.	—

Secondary

Measure	Time frame
1. To compare the requirement of opioids between groups. 2. To compare the complications between groups. 3. To compare the hemodynamic parameters between groups. 4. To compare the patient satisfaction score as per Likerts scale between groups. 5. To compare the disability by Hindi version of Oswestry Disability Index (Hi-ODI) between groups. 6. To compare the pre and post procedure CRP levels. Timepoint: Assessment done at pre procedure, during sheath placement phase, during inter vertebral disc removal phase, at the end of procedure and 1 week post operatively.	—

Measure

Time frame

1. To compare the requirement of opioids between groups. 2. To compare the complications between groups. 3. To compare the hemodynamic parameters between groups. 4. To compare the patient satisfaction score as per Likerts scale between groups. 5. To compare the disability by Hindi version of Oswestry Disability Index (Hi-ODI) between groups. 6. To compare the pre and post procedure CRP levels. Timepoint: Assessment done at pre procedure, during sheath placement phase, during inter vertebral disc removal phase, at the end of procedure and 1 week post operatively.

—

Countries

India

Contacts

Public ContactDr Sanjay Yadav

Institute of Medical Sciences, Banaras Hindu University

dranil1973@gmail.com9794855871

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026