Free flap reconstruction in head and neck oncosurgery defects.

Role of heparin in free flaps in head and neck micro vascular surgery: a randomized control trial

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090449

Enrollment

400

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Free flap surgery with Microvascular Anastomosis: Micro vascular free flap surgery which is most preferable method to reconstruct the head and neck defect in which anastomosis are done

Eligibility

Inclusion criteria

Inclusion criteria: Patient with head and neck oncosurgery defect who will need micro vascular surgery

Exclusion criteria

Exclusion criteria: Any patient with past history of anti platelet or anti coagulant Any patient who is already on DVT prophylaxis Any patient with Liver Disorders Any previous history of irradiated neck Infected neck

Design outcomes

Primary

Measure	Time frame
primary outcome from our center sample study was there was no clinical significant role of heparin in preventing microagulopathy in free flap post operativeTimepoint: Patient was evaluated at regular interval till POD 5 every 2 hourly.	—

Secondary

Measure	Time frame
Secondary outcomes like delayed flap necrosis & infection were noted during sample studyTimepoint: Detailed flap observation & clinical signs were evaluated till POD 21 every 5 days after discharged from hospital	—

Countries

India

Contacts

Public ContactHARDIK MEHTA

N M VIRANI WOCKHARDT HOSPITALS

mh2931996@gmail.com7016274019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026