To study the effect of an Ayurvedic Formulation in the form of eyedrops(yahtimadhu ghrita aschyothana)and an Ayurvedic formulation for nasal application(Anutaila Prathimarsha nasya)in patients having Dry Eye Disease

A Randomized open label clinical trial to evaluate the efficacy of Yashtimadhu ghrita Aschyothana and Anutaila Prathimarsha Nasya in Shushkakshipaka with special reference to Dry Eye Disease - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090442

Enrollment

Registered

2025-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H041- Other disorders of lacrimal gland

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients presenting with signs and symptoms of Dry eye Disease. 2.TBUT smaller than or equal to 5 seconds. 3.Schirmers test smaller than or equal to 10 mm.

Exclusion criteria

Exclusion criteria: 1. Cases complicated with acute, chronic, infective conjunctivitis or any specific eyelid disorder, corneal ulcer, dacryocystitis and lagophthalmos. 2. Contact lenses use. 3. History of ocular surgery within 6 months prior to enrolment in trial. 4. Pregnancy or child bearing age without contraception. 5. Patient who starts developing complications will be excluded from the study. 6. Patient not willing for the treatment. 7. Ongoing ocular or systemic infection. 8. Ocular or periocular malignancy. 9. Lid structural abnormality.

Design outcomes

Primary

Measure	Time frame
Change in Ocular Surface Disease Index(OSDI) score from baseline in parameters Change in Tear Film Break-up Time(TFBUT)Timepoint: Change in Ocular Surface Disease Index(OSDI) score from baseline in parameters Change in Tear Film Break-up Time(TFBUT) Assessed at 15th day,30th day and 45th day	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Mridulata Maurya

Banaras Hindu University

mridulata@bhu.ac.in9456914468

Outcome results